The Dow Jones Industrial Average was down 48.22 today, as markets cooled after a big rally last week. Some of the days biggest losers were as follows:

Isilon Systems, Inc. (ISLN) – Isilon Systems dropped nearly 10% today, or $2.36 on slightly above average volume. The stock traded at an intraday high of $24.61, and closed 26 cents above it’s intraday low of $21.84. There was no major news coming from Isilon that we are aware of.

Infinera Corp. (INFN) – Infinera Corp traded down 8.18% today, or $1.05 after a pre-market downgrade of the stock by Goldman Sachs to sell from neutral. The company makes digital telecommunications equipment, and closed close to the low of the day at $11.78.

M&T Bank Corporation (MTB) – M & T Bank closed the day at $84.24, down just over 7% on the day. The volume was over 2.5 times the normal daily volume. The stock gapped down to open $5 less than it’s closed at on Friday.

China Unicom (Hong Kong) Limited (CHU) – China Unicom traded down 5.87% today after Deutsche Bank maintained their sell rating on the stock. The trading range on the day for China Unicom was a high of $14.46 and a low of $14.25 after a gap down in the morning.